SigInt 1.0

SigInt 1.0 Screenshot SigInt is a command-line software utility that can be used to find and rank mammalian proteins/genes that specifically and significantly interact with a list of proteins/genes in context of a background mammalian signalome and interactome networks.

Developer:   Mount Sinai School of Medicine Iyengar Lab
      software by Mount Sinai School of Medicine Iyengar Lab →
Price:  0.00
License:   Freeware
File size:   0K
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OS:   Windows Vista (?)
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SigInt is a command-line software utility that can be used to find and rank mammalian proteins/genes that specifically and significantly interact with a list of proteins/genes in context of a background mammalian signalome and interactome networks.

The inputs to the program are:

  • a seed list of human Entrez Gene gene symbols,
  • a background networks in SIG format, and
  • a name for the output file (web-page file name with the htm extension)

    SigInt outputs a sorted list of genes/proteins that interacts with components from the seed list. These components are sorted by a z-score that measures the specificity of these intermediate components to interact with the genes/proteins from the seed list.

    tags seed list  from the  the seed  genes proteins  with the  interact with  proteins genes  

    SigInt 1.0 screenshot


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